California, United States·66K residents
South San Francisco is a city in San Mateo County, California, United States, on the San Francisco Peninsula in the San Francisco Bay Area. The city is colloquially termed "South City". The population was 66,105 as of the 2020 census, and was estimated at 64,941 in 2025.
How residents rate this city across 10 aspects
Be the first to review South San Francisco!